Deepthi s et al studied influence of silver nitrate and yeast extract on cell growth, camptothecin accumulation and cell viability and reported a significant increase in biomass and camptothecin production 20. These are primarily included because names of species rank are. Estimation of camptothecin and pharmacological evaluation of. Species of the genus contain camptothecin, an alkaloid used to make chemotherapeutic agents. Gaangaan, kalaikai, payangpayang 2 flemingia strobilifera linn. The ir spectrum indicated the presence of hydroxyl 3397 cm1, lactam carbonyl 1670 cm1 and aromatic functional 1596 cm1 groups. Gangan, kaliakai, kopakopa, paking, payangpayang, and 3 ophiorrhiza camiguinensis elm. Photoprotective potential in some medicinal plants used to.
Continuing to use this website means you agree to our use of cookies. Hptlcbased quantification of camptothecin in ophiorrhiza species. The plants database includes the following 1 species of ophiorrhiza. Cancer chemopreventive potential of luteolin7oglucoside isolated from ophiorrhiza mungos linn aa baskar, s ignacimuthu, gp michael, ks al numair nutrition and cancer 63 1, 8. The plant list includes 380 scientific plant names of species rank for the genus ophiorrhiza. Ophiorrhiza mungos is traditionally used in anticancer treatment in. Examining the relevant specimens reveals that it is a misidentification of o. Click below on a thumbnail map or name for species profiles.
Pdf camptothecin cpt, a cytotoxic quinoline indole alkaloid, is an anticancer compound. An efficient protocol has been established for rapid multiplication of ophiorrhiza mungos linn. General information about ophiorrhiza 1ophg this website uses cookies our website uses cookies to ensure that we give you the best possible online experience. They also noted that species of this genus are used as medicine for snakebites, stomach ulcers, skin eruptions, rheumatism, heart diseases, dye red, for wool and hair, and food the fruit, and list several. In this study, we evaluated for the first time the antiproliferation and antimigration effects of ethanol extract of o. Cancer chemopreventive potential of luteolin7oglucoside isolated from ophiorrhiza mungos linn aa baskar, s ignacimuthu, gp michael, ks al numair nutrition and cancer 63 1, 8, 2011. Control had the same composition but was free of extract. Camptothecinoids from the seeds of taiwanese nothapodytes. The genus ophiorrhiza comprises many medicinally important species such as o rugosa, o mungos, o hayatana, and o pumila. Estimation of camptothecin and pharmacological evaluation.
The highest free radical scavenging was shown by v. Enhanced camptothecin production induced by elicitors in the. S727 document heading estimation of camptothecin and pharmacological evaluation of ophiorrhiza prostrata d. The plant list includes a further 45 scientific plant names of infraspecific rank for the genus ophiorrhiza. Payangpayang is a common names of three different plants, of different genus. Cell suspension culture was established using the friable callus tissues induced from the field grown leaf explants cultured in ms solid media supplemented with 3 % sucrose, 3 mg l. Indian herbal snakebite cure scientifically validated. Molecules free fulltext camptothecinoids from the seeds of. Here, we evaluated the antiinflammatory and antimicrobial potency of 28 different extracts prepared from seven popular medicinal plant species employed in sri lanka. The ophiorrhiza mungos aqueous root extract neutralized the vipera russelli venom induced lethality and hemorrhage in fertile chick embryos. All structured data from the file and property namespaces is available under the creative commons cc0 license.
Organogenesis from leaf and internode explants of ophiorrhiza. Pharmacognostical studies on the leaves of ophiorrhiza mungos. The board of trustees of the royal botanic gardens, kew. The different tubes are filled with 1 ml of venom 100 gml, 1 ml phosphate buffer ph 7. Krishnakumar g1, rameshkumar kb2, priya srinivas3, satheeshkumar k1, krishnan pn1 1biotechnology and bioinformatics division 2phytochemistry and phytopharmacology division jawaharlal nehru tropical botanic garden. Ophiorrhiza wikispecies wikispecies, free species directory. Its representatives are found from tropical and subtropical asia to the pacific region. In the 1 hnmr spectrum of compound 2, the resonances and multiplicities largely matched those of the a, b.
The constant exposure to solar ultraviolet radiation uv has a variety of harmful effects on human health. Rubiaceae from the southern western ghats, kerala, india e. Traditional folk medicine in sri lanka is mostly based on plants and plantderived products, however, many of these medicinal plant species are scientifically unexplored. Ophiorrhiza macrocarpa rubiaceae, a new species from. Pharmacognostical studies on the leaves of ophiorrhiza mungos linn. Anticancer activity of ophiorrhiza species endemic to southern. Aug 09, 2011 an efficient system was developed for the in vitro micropropagation and hairy root culture of ophiorrhiza alata craib for camptothecin cpt production. Ophiorrhiza mungos was reported from china by several authors. The original may be consulted at royal college of physicians, london royal college of physicians, london clark, andrew, sir booklabel on pastedown. An ophiorrhiza in nahilalakip ha familia nga rubiaceae ilarom nga taxa. Micropropagation and hairy root culture of ophiorrhiza. Research article in vitro antioxidant and antiproliferative. Ophiorrhiza mungos is an erect, herbaceous, evergreen perennial plant with stems that can become more or less woody and persist.
Identified with tam kirippuu, kirippuraa identified with mal avilpori. Accordingly, we formally transferred all validly published names from keenania and spiradiclis to ophiorrhiza, resulting in 40 new combinations and 15 new names. Salvadoraceae locally known as mulsangu, is a spinous shrub flowering throughout the year found in peninsular india, west bengal, orissa, african countries and. The record derives from wcsp data supplied on 20120323 which reports it as an accepted name record 140493 with original publication details. Bungarus caeruleus venom neutralization activity of azima. This page was last edited on 19 december 2019, at 02. The ones marked may be different from the article in the profile. World checklist of selected plant families database in access.
Antitumor activities of an anthraquinone fraction isolated. Pdf on jan 1, 20, varadharajan madhavan and others. Krishnakumar g1, rameshkumar kb2, priya srinivas3, satheeshkumar k1, krishnan pn1 1biotechnology and bioinformatics division 2phytochemistry and phytopharmacology division jawaharlal nehru tropical botanic garden and research institute palode. Nov, 2015 production of camptothecin cpt, an anticancer compound was enhanced in the cell suspension cultures of ophiorrhiza mungos linn. Ophiorrhiza mungoszwickau et addenda this material has been provided by royal college of physicians, london. Ophiorrhiza is a genus of flowering plants in the coffee family rubiaceae.
Rapid plant regeneration, analysis of genetic fidelity and. Anticancer activity of ophiorrhiza species endemic to. Ophiorrhiza is a genus of flowering plants in the coffee family. Ophiorrhiza wallichii was originally described in india and later reported as new record in china. Although synthetic sunscreen products have been introduced as a preventivetherapeutic strategy, with the realization of their adverse side effects, the recent trend is to search for human friendly alternative formulations especially of plant origin. Apr, 2019 ophiorrhiza is paraphyletic with respect to keenania and spiradiclis, and was resolved in two well. Ophiorrhiza macrocarpa rubiaceae, a new species from yunnan, southwestern china. Ethanol extract of ophiorrhiza pumila suppresses liver cancer. We do not use these to store personal information about you. They also noted that species of this genus are used as medicine for snakebites, stomach ulcers, skin eruptions, rheumatism, heart diseases, dye red, for wool and. Text is available under the creative commons attributionsharealike license.
Plants in genus ophiorrhiza shows the presence of significant amount of camptothecin. Polyphyly of pomazoteae and paraphyly of ophiorrhizeae and ophiorrhiza. Although ophiorrhiza leptantha and ophiorrhiza laxa have been combined by some authors, they are with very few exceptions readily distinguished by number and size of flowers, amount and colour of calycine indument, and staminal characters. Pdf pharmacognostical studies on the leaves of ophiorrhiza. Leaves 715 x 36 cm, elliptic or ellipticlanceolate, base attenuate, apex acuminate, chartaceous, hirsute on veins below. Although ophiorrhiza leptantha and ophiorrhiza laxa are sometimes essentially sympatric within fiji, the.
Among the ophiorrhiza species, ophiorrhiza mungos contains the highest cpt level 0. Micropropagation and hairy root culture of ophiorrhiza alata. Production of camptothecin cpt, an anticancer compound was enhanced in the cell suspension cultures of ophiorrhiza mungos linn. Ophiorrhiza laxa is a copiously branched, evergreen perennial plant with stems that are more or less woody. Save nature to survive phytochemical analysis and evaluation. Mitreola boehm mungos adans notodontia pierre ex pit especies. Shoot multiplication on leaf and node explants from germinated seeds of o. Identified with eng mongoose plant, indian snake root. We do not intend the plant list to be complete for names of infraspecific rank. Files are available under licenses specified on their description page. Excluding ophiorrhiza mungos rubiaceae from flora of. Ophiorrhiza is paraphyletic with respect to keenania and spiradiclis, and was resolved in two well.
Ophiorrhiza mungos wikispecies, free species directory. The plant is a promising candidate for continue reading. Enhanced camptothecin production induced by elicitors in. Pyrenacantha klaineaqna icacinaceae 4, ophiorrhiza mungos 5, ophiorrhiza pumila, ophiorrhiza filistipula 6, ophiorrhiza trichocarpon. Ophiorrhizeae is a tribe of flowering plants in the family rubiaceae and contains about 364 species in 4 genera. Research article in vitro antioxidant and antiproliferative potential of medicinal plants used in traditional indian medicine to treat cancer arulalbert baskar1, khalids. Ophiorrhiza mungos zwickau et addenda this material has been provided by royal college of physicians, london. Thiruvananthapuram a herb, long used in traditional indian ayurvedic medicine to treat snakebite, has been proven in studies on chick embryos to contain compounds that can neutralise viper venom, says a new study. It can grow from 20 300cm tall, and is often compact 490. They also noted that species of this genus are used as medicine for snakebites, stomach ulcers, skin eruptions. Alsaif1, savarimuthu ignacimuthu2 1department of community health sciences, college of applied medical sciences, king saud university, riyadh, saudi arabia, 2division of.
However, the specimens and literature revealed that o. Ophiorrhiza pumila, belonging to the genus ophiorrhiza rubiaceae, is distributed throughout tropical and subtropical asia. Researchers at the kerala university ku, thiruvananthapuram, found that the root extract of ophiorrhiza mungos locally known as mongoose plant can. The biological effects of the anthraquinone fraction aqf isolated from in vitro cultures of ophiorrhiza rugosa wall. An efficient system was developed for the in vitro micropropagation and hairy root culture of ophiorrhiza alata craib for camptothecin cpt production. This cited by count includes citations to the following articles in scholar. The extracts were subjected to cellbased and cell free. Ethanol extract of ophiorrhiza pumila suppresses liver. So many of ophiorrhiza species are endemic to certain areas of western ghats. Excluding ophiorrhiza mungos rubiaceae from flora of china. Habitat khasi hills up to 600700 m, in western ghats and the andaman islands. Studies on neutralizing effect of ophiorrhiza mungos root.
1418 282 1040 798 191 199 2 209 213 1567 1534 427 696 61 622 602 248 1462 1068 883 202 1417 821 701 1092 383 1276 185 637 1008 50 571 1076 513 228 1516 240 840 1101 337 85 413 830 1122 690